Sainte-Monique is an unincorporated community in Quebec, Canada. It is recognized as a designated place by Statistics Canada.
In the 2021 Census of Population conducted by Statistics Canada, Sainte-Monique had a population of 194 living in 78 of its 81 total private dwellings, a change of from its 2016 population of 200. With a land area of , it had a population density of in 2021.