Sainte-Florence (;) is a Canadian forestry village in the province of Quebec, located in the Matapédia Valley in the Gaspé Peninsula.
The municipality had a population of 367 as of the Canada 2021 Census.
In the 2021 Census of Population conducted by Statistics Canada, Sainte-Florence had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.
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