Saint Antoine l'Abbaye (, before 1991: Saint-Antoine), also Saint-Antoine-en-Viennois, is a commune in the Isère department in southeastern France. On 31 December 2015 the former commune of Dionay was merged into Saint Antoine l'Abbaye.
Formerly known as La-Motte-Saint-Didier, it was renamed after becoming the home of purported relics of Saint Anthony the Great in the 11th century, and shortly afterwards of the original house of the Hospital Brothers of St. Anthony, founded here in 1095 as the result of miraculous cures from St. Anthony's Fire ascribed to the relics.
It was established as a Benedictine community, with monks responsible for the care of the shrine and its relics, while the Brothers tended to those suffering from St. AnthonyâÂÂs fire, a condition common at the time. Over the course of the next two centuries, disputes between the Antonines and the Benedictines arose repeatedly. The Antonines were formed into an Order of canons regular in 1297. At that time the Benedictine monks were removed from the shrine, which was entrusted to the Antonines. In 1890, the Canons Regular of the Immaculate Conception were given the Abbey of St. Antony, which was the motherhouse of the congregation. It maintained that role from 1890 until 1903, when, following the anti-clerical laws passed by the French government in 1901, the community was transferred to Andora, in the Italian region of Liguria.
In July 2025, an annual France 2 series, "Le Village préféré des Français", named the village as most popular amongst the French.
The town is situated on the right bank of the Furand River, on a molasse formation resulting from the Alpine orogeny. The town's main monuments (notably the abbey buildings and the town hall) make extensive use of this rock, which is well-suited to sculpture.
Since 2009, the village has been a member of Les Plus Beaux Villages de France (The Most Beautiful Villages of France) Association and hosts many monuments, the most important of which are the Abbey Church and the abbey.
Saint Antoine l'Abbaye is twinned with: