Saint-Pern (; ; Gallo: Saent-Pèrn) is a commune in the Ille-et-Vilaine department in Brittany in northwestern France.
Saint-Pern is the burial place of Saint Jeanne Jugan, where the motherhouse of the Little Sisters of the Poor at La Tour St. Joseph is located.
Inhabitants of Saint-Pern are called saint-pernais in French.