Saba Talpur () is a Pakistani politician from Umerkot who is a member-elect of the National Assembly of Pakistan.
Talpur was elected to the National Assembly of Pakistan in a 2025 by-election from NA-213 Umerkot as a candidate of Pakistan People's Party (PPP). The by-election was called due to the death of Nawab Yousuf Talpur, her husband. She received 161,934 votes and defeated Lal Chand Malhi, an independent candidate supported by Pakistan Tehreek-e-Insaf (PTI).