SAP130

Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene.

Function

SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM]

Interactions

SAP130 has been shown to interact with:

• CSN1S1,
• CUL2,
• Myc,
• SIN3A, and
• Von Hippel–Lindau tumor suppressor and

References

Further reading