Rupsa () is an upazila of Khulna District in the Division of Khulna, Bangladesh.
Rupsa is located at . It has 41,895 households and total area 120.15 km<sup>2</sup>.
According to the 2022 Bangladeshi census, Rupsa Upazila had 52,457 households and a population of 206,748. 9.00% were under 5 years of age. Rupsa had a literacy rate of 80.04%: 81.65% for males and 78.44% for females, with a sex ratio of 99.68 males per 100 females. 38,159 (18.45%) lived in urban areas.
As of the 2011 Census of Bangladesh, Rupsa upazila had 41,895 households and a population of 179,519. 35,583 (19.82%) were under 10 years of age. Rupsa had an average literacy rate of 58.23%, compared to the national average of 51.8%, and a sex ratio of 990 females per 1000 males. The entire population was rural.
According to the 1991 Bangladesh census, Rupsa had a population of 150,185. Males constituted 51.98% of the population and females 48.02%. The population aged 18 or over was 77,918. Rupsa had an average literacy rate of 40.4% (7+ years), compared to the national average of 32.4%.
Rupsa Upazila is divided into five union parishads: Aichgati, Ghatvog, Noihati, Srifoltola, and T. S. Bahirdia. The union parishads are subdivided into 64 mauzas and 78 villages.