Rosario de la Frontera is a city in the center-south of the province of Salta, Argentina. It has 26,174 inhabitants as per the , and is the head town of the Rosario de la Frontera Department. It is located on National Route 9, by the Horcones River.
Rosario de la Frontera has a dry-winter humid subtropical climate (Köppen Cwa), characterised by very warm and uncomfortably humid summers alongside pleasant to warm, dry winters with cold mornings and occasional frosts.