Ropes Creek, a watercourse that is part of the Hawkesbury-Nepean catchment, is located in Greater Western Sydney, New South Wales, Australia.
Ropes Creek rises in the south-western suburbs of Sydney, near Devils Back Tunnel, about north north-east of . The creek flows generally north before reaching its confluence with South Creek, in the suburb of , north of the Wianamatta Regional Park. The creek descends over its course.
Ropes Creek is transversed by the Westlink M7 at Cecil Park; the M4 Western Motorway between and ; and the Great Western Highway and the Main Western railway line east of .
The creek in named in honour of Anthony Rope, a First Fleet convict who it is assumed was granted land fronting the creek.
Part of surrounding area to the north-west professionally assessed for its ecological values in 2015, documenting occurrences of threatened species.