Romania competed at the 2020 Summer Paralympics in Tokyo, Japan, from 24 August to 5 September 2021. The Romanian delegation consisted of seven athletes, six men and one woman. The delegation won two medals, a silver in cycling and one in Judo, placing 65th in a four-way tie.
Originally scheduled to take place in Tokyo, Japan from 24 July to 9 August 2020, the Games were postponed due to the COVID-19 pandemic. They were eventually played in Tokyo from 24 August through 5 September 2021.
The Romania delegation consisted of seven athletes, six men and one woman.
The Romanian delegation won two medals, one silver and one bronze, finishing in a joint 65th place in the medal table alongside the delegations of Kuwait, Namibia, and Slovenia.
Romania sent one cyclist, Minister for Youth and Sport Carol-Eduard Novak, after successfully getting a slot in the European 2018 UCI Nations Ranking Allocation quota. Novak won a silver medal in Men's C4 4000 meter individual pursuit after losing to Jozef Metelka.
Romania sent one cyclist, Alex Bologa. Bologa won a bronze medal in Men's 60 kilograms. Baloga had previously won in an upset at the same event at the 2016 games being awarded a bronze medal. The event was held at the Nippon Budokan arena.
Romania entered one athlete, Bobi Simion, into the table tennis competition at the games. Simion qualified via the World Ranking allocation. He lost in the quarter finals. Simion had previously represented Romania in the 2016 games where he also lost in the quarter finals.