Roman Prymula (born 4 February 1964) is a Czech physician, professor of epidemiology, and a retired army colonel.
During the early stages of the COVID-19 pandemic in the Czech Republic, he served as the head of the Czech government's Central Crisis Board () and then as a government agent for science and research. On 21 September 2020 he was named as Minister of Health of the Czech Republic by Prime Minister Andrej Babià ¡ following the resignation of Adam VojtÃÂch.
On 21 October 2020, the tabloid Blesk published photographs of Prymula and Jaroslav Faltýnek leaving a restaurant late at night in apparent breach of COVID-19 regulations, under which all restaurants were supposed to be closed. He was replaced by Jan Blatný on 29 October.