The Diocese of Azcapotzalco (Latin: Dioecesis Azcapotzalcensis) is a Latin Church ecclesiastical territory or diocese of the Catholic Church in Mexico.
It was erected on 28 September 2019 with its territory having been carved from the Archdiocese of Mexico. The diocese is a suffragan in the ecclesiastical province of the metropolitan Archdiocese of Mexico and covers 59 parishes with 850,000 Catholics.