The Roman Catholic Metropolitan Archdiocese of Santiago de los Caballeros () is a Latin Rite Metropolitan Archdiocese in the Dominican Republic.
As per 2014, it pastorally served 1,118,000 Catholics (83.7% of 1,336,000 total) on 3,633 kmò in 89 parishes and 17 missions with 125 priests (74 diocesan, 51 religious), 132 deacons, 350 lay religious (136 brothers, 214 sisters) and 37 seminarians.
The Metropolitan has the following suffragan sees :
(all Roman Rite)