Rock Spring Run is a long 1st order tributary to the Youghiogheny River in Fayette County, Pennsylvania.
According to the Geographic Names Information System, it has also been known historically as:
Rock Spring Run rises about 2.5 miles north-northeast of Victoria, Pennsylvania, and then flows southwest to join the Youghiogheny River at Victoria.
Rock Spring Run drains of area, receives about 47.9 in/year of precipitation, has a wetness index of 381.95, and is about 94% forested.