Rentina () is a village and a former municipality in the Karditsa regional unit, Thessaly, Greece. Since the 2011 local government reform it is part of the municipality Sofades, of which it is a municipal unit. The municipal unit has an area of 56.968 km<sup>2</sup>. Population 261 (2021). The village has been identified as the site of the ancient city of Ctimene.
Rentina is the birthplace of Greek Prime Minister Georgios Tsolakoglou (1886-1948).