Reese is an unincorporated community and census-designated place (CDP) in Blair County, Pennsylvania, United States. It was first listed as a CDP prior to the 2020 census.
The CDP is in east-central Blair County, in the eastern part of Frankstown Township. It sits on the north side of the Frankstown Branch Juniata River, east of Hollidaysburg, the county seat, and southwest of Canoe Creek.
The school district is Hollidaysburg Area School District.