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Rate of infusion

In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective.

Abbreviations include K<sub>in</sub>, K<sub>0</sub>, or R<sub>0</sub>.

It can be calculated as the steady-state concentration in the plasma multiplied by the clearance:

References