The R576 is a Regional Route in Limpopo, South Africa that connects Codrington with Settlers.
Its western terminus is a junction with the R101 at Codrington, approximately 18 kilometres south of Bela-Bela (Warmbaths) and 18 kilometres north of Pienaarsrivier. It heads east-north-east for 22 kilometres, crossing the N1 freeway, to end at an intersection with the R516 just west of Settlers.