The R568 is a Regional Route in South Africa that connects Siyabuswa with Bronkhorstspruit via KwaMhlanga.
Its north-eastern terminus is an intersection with the R573 at Siyabuswa, Mpumalanga. It initially heads west, then south-west, again crossing the R573 at KwaMhlanga. It then heads south, passing through Loopspruit before crossing into Gauteng and passing through Ekangala. South of Ekangala, it co-signs with the R513 for 2.5 kilometres and then crosses the R104 and N4 highway (Maputo Corridor) just west of Bronkhorstspruit. It then ends at an intersection with the R25.