The R306 is a Regional Route in South Africa that connects the N9 between Willowmore and Aberdeen with the R61 between Beaufort West and Aberdeen.
The R306 begins at a junction with the N9 route approximately 18 kilometres north of Willowmore in the Eastern Cape. It heads in a north-westerly direction for 110 kilometres, through Rietbron, crossing into the Western Cape, to reach its end at a junction with the R61 route approximately 18 kilometres east of Beaufort West.