Qosqophryne is a genus of strabomantid frogs. These frogs are endemic to south-eastern Peru in the Cusco Region at 3270 to 3800 meters above sea level. A phylogenetic analysis found Qosqophryne as sister to the genus Microkayla and that this clade was more closely related to Noblella and Psychrophrynella than to other species in Bryophryne.
The genus Qosqophryne was erected in 2020 to accommodate three species that were in Bryophryne at that time.
The following species are recognised in the genus Qosqophryne: