Qiannan Buyei and Miao Autonomous Prefecture (; Buyei: Qianfnanf Buxqyaix Buxyeeuz ziqziqzouy; Hmu: Qeef Naif Dol Yat Dol Hmub Zid Zid Zeb) is an autonomous prefecture of Guizhou province, People's Republic of China, bordering Guangxi to the south. The prefecture's seat is Duyun, while its area is . The name "" derives from the prefecture's south-central location in the province; "" is the official abbreviation for Guizhou, while "" means "south".
Qiannan Buyei and Miao Autonomous Prefecture is located in southern Guizhou and situated between 106ð12âÂÂâÂÂ108ð18â E longitude and 25ð04âÂÂâÂÂ27ð29â N. The southernmost point of the prefecture, in Libo County, is the closest point in Guizhou to the coast, approximately 390 km from Fangchenggang (Guangxi). Qiannan borders Qiandongnan Miao and Dong Autonomous Prefecture (Guizhou) to the east, Hechi (Guangxi) to the south, Anshun and Qianxinan Buyei and Miao Autonomous Prefecture (Guizhou) to the west, and Zunyi and Guiyang (Guizhou) to the north and northwest. The total area of the prefecture is 26,192 km<sup>2</sup> (10,113 sq mi).
According to the 2000 Census, Qiannan Prefecture had 3,569,847 inhabitants with a population density of 136.22 inhabitants/km<sup>2</sup>; at the 2010 Census, it had 3,232,714 inhabitants.
The prefecture is subdivided into 12 county-level divisions: 2 county-level cities, 9 counties, and 1 autonomous county.