Pylaia-Chortiatis () is a municipality in the Thessaloniki regional unit, Central Macedonia, Greece, consisting of three suburbs of Thessaloniki. The seat of the municipality is Panorama. The municipality has an area of 155.63 km<sup>2</sup>.
The municipality Pylaia-Chortiatis was formed at the 2011 local government reform by the merger of the following 3 former municipalities, that became municipal units: