Puyusca (Quechua: Phuyusqa, meaning "cloudy") is one of eight districts of the Parinacochas Province in Peru.
One of the highest elevations of the district is glacier-covered Sara Sara volcano at . Other mountains are listed below:
The people in the district are mainly indigenous citizens of Quechua descent. Quechua is the language which the majority of the population (62.54%) learnt to speak in childhood, 36.97% of the residents started speaking using the Spanish language (2007 Peru Census).