Pueblo Nuevo is a municipality in the Mexican state of Durango. The municipal seat lies at El Salto. The municipality covers an area of 6178.3 km<sup>2</sup>.
The village of Pueblo Nuevo was the seat of government of the municipality before the 1920s. The village is on the new four-lane highway route between Durango, Durango, and Mazatlán, Sinaloa, and is likely to see expanding tourist traffic due to its proximity to the Baluarte Bridge.
In 2010, the municipality had a total population of 49,162.
The municipality had 543 localities. As of the 2010 census, the largest are El Salto (24,241), La Ciudad (2,693),San Bernardino de Milpillas Chico,(9,74).