Ptychochromoides vondrozo is a critically endangered species of cichlid endemic to the Mananara-sud river and its tributaries near Vondrozo in southeastern Madagascar. These are deep and moderate to fast-flowing. Its entire range covers less than , which makes it highly threatened from continued sedimentation caused by deforestation. It is also threatened by other species that have been introduced to the region. It reaches a length of SL.