Pryazhinsky District (; ) is an administrative district (raion), one of the fifteen in the Republic of Karelia, Russia. It is located in the south of the republic. The area of the district is . Its administrative center is the urban locality (an urban-type settlement) of Pryazha. As of the 2010 Census, the total population of the district was 14,664, with the population of Pryazha accounting for 25.1% of that number.
Within the framework of administrative divisions, Pryazhinsky District is one of the fifteen in the Republic of Karelia and has administrative jurisdiction over one urban-type settlement (Pryazha) and eighty-one rural localities. As a municipal division, the district is incorporated as Pryazhinsky Municipal District. The urban-type settlement of Pryazha and three rural localities are incorporated into an urban settlement, while the remaining seventy-eight rural localities are incorporated into six rural settlements within the municipal district. The urban-type settlement of Pryazha serves as the administrative center of both the administrative and municipal district.