Prusice () is a town in Trzebnica County, Lower Silesian Voivodeship, in south-western Poland. It is the seat of the administrative district (gmina) called Gmina Prusice.
As of 2019, the town has a population of 2,243.
Prusice lies approximately north of the regional capital Wrocà Âaw.
Prusice was mentioned as a market settlement with a church in 1253. It was granted town rights in 1287 by Duke Henry Probus. It was ravaged by the Hussites in 1432. Following the Reformation, the local church was Lutheran from 1594 to 1654. The town suffered during the Thirty Years' War in 1640âÂÂ1642. In 1842, the town had a population of 2,429.
Among the historic sights of Prusice are the Market Square (Rynek), the Renaissance Town Hall (') and the churches of St. James and St. Joseph.
Prusice is bypassed to the west by the S5 expressway. Exits 55 and 54 of the expressway provide quick access to Poznaà  and Wrocà Âaw.
The nearest railway station is to the west in the village of Skokowa.
See twin towns of Gmina Prusice.