Proserpio (Brianzöö: ) is a comune (municipality) in the Province of Como in the Italian region Lombardy, located about north of Milan and about east of Como. As of 31 December 2004, it had a population of 942 and an area of . The name comes from the Roman goddess Proserpina.
Proserpio borders the following municipalities: Canzo, Castelmarte, Erba, Longone al Segrino.