The gray-footed spiny rat (Proechimys poliopus) is a species of rodent in the family Echimyidae. It is found in Colombia and Venezuela.
Morphological characters and mitochondrial cytochrome b DNA sequences showed that P. poliopus belongs to the so-called trinitatus group of Proechimys species, and shares closer phylogenetic affinities with the other members of this clade: P. trinitatus, P. mincae, P. guairae, P. magdalenae, P. chrysaeolus, P. urichi, and P. hoplomyoides.