Potassium hexafluorophosphate is a chemical compound with the formula KPF<sub>6</sub>. This colourless salt consists of potassium cations and hexafluorophosphate anions. It is prepared from phosphorus pentachloride:
This exothermic reaction is conducted in liquid hydrogen fluoride. The salt is stable in a hot alkaline aqueous solution, from which it can be recrystallized. The sodium and ammonium salts are more soluble in water whereas the rubidium and caesium salts are less so.
KPF<sub>6</sub> is a common laboratory source of the hexafluorophosphate anion, a non-coordinating anion that confers lipophilicity to its salts.