Port Glasgow Upper was a railway station serving Port Glasgow, Renfrewshire, Scotland, originally as part of the Greenock and Ayrshire Railway.
The station was opened on 23 December 1869. On 2 February 1959, stopping passenger services from Glasgow and Paisley ceased running beyond Kilmacolm; however, the boat trains continued running, without stopping, until 30 November 1965.
Port Glasgow Harelaw telephone exchange, a children's home and a care home for elderly people now stand on the site.