Ponzano di Fermo is a comune (municipality) in the Province of Fermo in the Italian region Marche, located about south of Ancona and about north of Ascoli Piceno. As of 31 December 2004, it had a population of 1,623 and an area of .
The municipality of Ponzano di Fermo contains the frazione (subdivision) Torchiaro e Capparuccia.
Ponzano di Fermo borders the following municipalities: Fermo, Grottazzolina, Monte Giberto, Monterubbiano, Petritoli.