Pontecchio Polesine is a comune (municipality) in the Province of Rovigo in the Italian region Veneto, located about southwest of Venice and about southeast of Rovigo. On 1 January 2019, it had a population of 2,191 and an area of .
The municipality of Pontecchio Polesine contains the frazioni (subdivisions, mainly villages and hamlets) Borgo, Busi, Ca'Zanforlin, Chiaviche Roncagalle, L'Olmo, and Selva.
Pontecchio Polesine borders the following municipalities: Bosaro, Crespino, Guarda Veneta, Rovigo.
Adelmo Landini was born in Pontecchio Polesine in 1896. He moved to Bologna to obtain a technical license, and later served in the Italian army during World War I. Landini died in August 1965, and the Municipality of Sasso named a street for him near the Marconi Museum and Mausoleum.