Pirson or Pirsson is a surname. Notable people with the surname include:
- André-Eugène Pirson (1817âÂÂ1881), Belgian liberal politician, civil servant, and former governor of the National Bank of Belgium
- James W. Pirsson, AIA, (1833âÂÂ1888), American architect and a founder of a New York City architectural firm
- Sören Pirson (born 1985), German footballer
See also