Wise River is an unincorporated community in northern Beaverhead County, Montana, United States. As of the 2020 census, Wise River had a population of 42.
This community takes its name from the Wise River, which flows into the Big Hole River nearby. A post office was established in 1913.
The Elkhorn-Coolidge Historic District on the National Register of Historic Places is nearby. The district includes the Elkhorn mine site and the ghost town of Coolidge. The mine was for silver and began operation in 1872.
Wise River has a subarctic climate (Köppen Dfc).
Wise River provides elementary education. High school is at Beaverhead County High School.