San Canzian d'Isonzo (Bisiacco: ; ; ) is a (municipality) in the Regional decentralization entity of Gorizia in Friuli-Venezia Giulia, northeast Italy.
The small town is situated about from Gorizia, the capital of the province, and west of the important port of Trieste. Its name refers to the martyrs Cantius, Cantianus, and Cantianilla, who are said to have been beheaded here in 304 AD.
It is also the birthplace of Italian footballer and former AC Milan manager Fabio Capello.