Pfeiffer-Wheeler American Chestnut Cabin is a historic log cabin located at the Pfeiffer Nature Center, Portville in Cattaraugus County, New York. It is a log cabin constructed of American Chestnut in 1941. It is thought to be one of very few examples of a private residence utilizing American chestnut log frame construction from this period.
It was listed on the National Register of Historic Places in 2002.