Perryville High School is a public secondary school in Perryville, Maryland, United States. The school is operated by Cecil County Public Schools. Enrollment for 2015 is reported as 810 students.
In 2016, the Perryville Panthers completed an undefeated season in softball to win the state championship. June 7 was made the Perryville High School softball team day in honor of this accomplishment.
Perryville High School's marching band has 10 straight Maryland state 1A Championship titles and many other awards.