Peptidyl-dipeptidase B (, dipeptidyl carboxyhydrolase, atriopeptin convertase, atrial di-(tri)peptidyl carboxyhydrolase, peptidyldipeptidase B, atrial dipeptidyl carboxyhydrolase, atrial peptide convertase) is an enzyme. It catalyses the following chemical reaction
This membrane-bound, zinc metallopeptidase is located in mammalian atrial myocytes.