Peperomia tuisana is a species of perennial, lithophyte or epiphyte from the genus Peperomia. It was first described by Casimir de Candolle and published in the book "Anales del Instituto FÃÂsico-Geográfico y del Museo Nacional de Costa Rica 9: 176. 1896[1898] ". It primarily grows on wet tropical biomes. The species name came from Tuis, where first specimens of this species were collected.
It is endemic to Central and Mexico. First specimens were found at an altitude of in Tuis.