Peperomia tetraquetra is a species of hemiepiphytic subshrub from the genus Peperomia. It was first described by Luis Sodiro and published in the book "Contribuciones al conocimiento de la Flora Ecuatoriana . . . Monografia i. Piperaceas Ecuatorianas 1: 175. 1900 ". It primarily grows on wet tropical biomes.
It is endemic to Southern America. First specimens where found at an altitude of 2787.5 meters in Lara