Pender Murphy (born March 19, 1959) is a former professional tennis player from United States.
Murphy grew up in Charlotte, North Carolina and attended Clemson University, where he earned All-American honors on three occasions.
Following his time at Clemson University he competed professionally for two years. His best result on the Grand Prix tour was a semi-final appearance at Venice in 1982, after which he reached a career best ranking of 102 in the world. He competed in the main draw of two Grand Slam tournaments, the 1982 US Open and 1983 French Open.