PekwüxeêÂÂyles or Peckquaylis is an Indian reserve on the north bank of the Fraser River in Mission, British Columbia, Canada, located between Lower Hatzic Slough and D'Herbomez Creek.
PekwüxeêÂÂyles is 10.3 hectares large. The Fraser Valley Child Development Centre has satellite offices on the reserve.
The reserve was reinstated in June 2005 by Order in Council. It sits on the former site of St. Mary's Indian Residential School. The 2023 three-day Walk in the Spirit of Reconciliation concluded at the St. Mary's Indian Residential School site in Mission on the Pekw'Xe:yles Reserve.
The reserve is used by 21 First Nation band governments. They are as follows.