Patterson's Archeological District is a archaeological site near Wallville in Calvert County, Maryland at the mouth of St. Leonard's Creek, the largest tributary of the tidal portions of the Patuxent River. It contains a representative sample of a range of archeological sites characteristic of both upland and lowland utilization of the Chesapeake Bay tidewater region during the prehistoric and historic periods. The property also contains a range of historic sites.
It was listed on the National Register of Historic Places in 1982. This district is a component of Jefferson Patterson Park & Museum.