Patrick Mayo (born 15 May 1973) is a retired South African association football midfielder who most recently served as an assistant coach to Chippa United's MultiChoice Diski Challenge team. He made 18 appearances for the Bafana Bafana and played at the 2004 African Cup of Nations.
Mayo is the father of Khanyisa Mayo.
While playing for Kaizer Chiefs, Fredericks scored one of the goals in the final of the 2003 Coca-Cola Cup, at the time the richest cup tournament in Africa.