Patrick MacDonald (born February 20, 1982) is a Canadian former professional football player who was a defensive lineman in the Canadian Football League (CFL). He was signed by the New Orleans Saints as an undrafted free agent in 2007 and was the second player in the school's history to go to the NFL. He was selected by the Calgary Stampeders in the third round of the 2007 CFL draft. He played college football at University of Alberta.
MacDonald was also a member of the Carolina Panthers, Winnipeg Blue Bombers, Seattle Seahawks and Montreal Alouettes, winning a Grey Cup in 2008 and 2010.
Patrick MacDonald is now an entrepreneur and youth football coach living in Victoria, Canada with his family.