Pasquale Pozzessere (born in 1957) is an Italian film director and screenwriter.
Born in Lizzano, Taranto in the mid-1980s Pozzessere abandoned his medicine university studies to enter the cinema industry working as a script supervisor for Pupi Avati and as assistant director of Francesco Maselli. After directing a number of short films, he made his feature film debut in 1992, with Verso Sud, for which he was nominated to a David di Donatello for Best New Director and won the Grolla d'oro in the same category. The film also won the Grand Prix at the Annecy Film Festival.