The Papua New Guinea cricket team toured Oman in September 2021 to play two One Day International (ODI) matches against Nepal and two ODI matches against the United States. The matches were used as preparation for all three teams ahead of the Cricket World Cup League 2 series, also in Oman, which started on 13 September 2021 and 25 September 2021 respectively.
In the first round of matches, the United States beat Papua New Guinea by seven wickets, with Nepal beating Papua New Guinea by two wickets in the second match. The United States won their second match against Papua New Guinea by 134 runs, with Jaskaran Malhotra scoring the first century for the United States in an ODI match. The final match saw Nepal beat Papua New Guinea by 151 runs, leaving Papua New Guinea winless across all four matches.
The United States also named Kyle Phillip as a travelling reserve player for the tour.