Panepistimio (, , ) is a metro station serving Thessaloniki Metro's Line 1 and Line 2. The station is named after the Aristotle University of Thessaloniki and the adjacent University of Macedonia. Construction of the station was delayed by major archaeological finds, and it is designated as a mid-importance archaeological site by Attiko Metro, the company overseeing its construction. It entered service in 2024.
Panepistimio station appears in the 1988 Thessaloniki Metro proposal, and construction of a section of the system began here in the same year before being abandoned due to lack of funding.